Adrenal Fatigue Check2023-11-29T22:21:26+00:00

Adrenal Fatigue Check

Adrenal Fatigue Check

Simply Hormone Adrenal Fatigue Test Kit

SimplyHormone™: Adrenal Fatigue Check

  • Cortisol x4 + DHEA

  • Physician ordered testing

  • Male or Female

  • Noninvasive, pain-free saliva specimen collection

  • Free Shipping

  • Results in 24-48 hours after received at the lab

  • Consistent, highly accurate, & dependable molecular testing

  • Actionable clinical insights

  • Saliva testing is less expensive than conventional serum testing

  • CAP/CLIA accredited testing laboratory

WHY CHOOSE
SIMPLY HORMONE?

WHY CHOOSE
SIMPLY HORMONE?

Patients prefer the pain-free, non-invasive, and ease-of-use saliva testing offers. Unlike blood testing, hormone testing using saliva is not only easy and pain-free, it also has the unique ability through sensitive molecular testing to accurately measure the current bioavailable amount of hormone available to your body’s target tissues. For this reason, saliva testing better relates to specific symptoms of excess and deficiency.

  • Saliva testing is a consistent, highly accurate, & dependable method for measuring free testosterone levels.¹
  • Saliva can be used in a clinical setting to diagnose and monitor treatment of hormonal disorders.²
  • SimplyTest saliva sample preservation buffer increases test precision, accuracy, and assay reproducibility.³
  • Saliva collection avoids the stress impact a blood draw can have on hormone levels.
  • Reports demonstrate an increase in overall test participation & ongoing compliance with frequent testing regimens when saliva is offered.⁴

[1] Keevil, B. G., MacDonald, P., Macdowall, W., Lee, D. M., Wu, F. C., & NATSAL Team (2014). Salivary testosterone measurement by liquid chromatography tandem mass spectrometry in adult males and females. Annals of clinical biochemistry, 51(Pt 3), 368–378. https://doi.org/10.1177/0004563213506412[2] Hammerich, K. H., Donahue, T. F., Rosner, I. L., Cullen, J., Kuo, H. C., Hurwitz, L., Chen, Y., Bernstein, M., Coleman, J., Danila, D. C., & Metwalli, A. R. (2017). Alkaline phosphatase velocity predicts overall survival and bone metastasis in patients with castration-resistant prostate cancer. Urologic oncology, 35(7), 460.e21–460.e28. https://doi.org/10.1016/j.urolonc.2017.02.001[3] Alimetrix 2023, Testosterone Assay Validation Summary[4] Dhima, M., Salinas, T. J., Wermers, R. A., Weaver, A. L., & Koka, S. (2013). Preference changes of adult outpatients for giving saliva, urine and blood for clinical testing after actual sample collection. Journal of prosthodontic research, 57(1), 51–56. https://doi.org/10.1016/j.jpor.2012.09.004

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Meet the Lab

FAQ’s

Frequently Asked Questions

What is the importance of understanding your patients’ cortisol levels?2023-05-04T16:57:05+00:00

Understanding a patient’s cortisol levels is important to diagnose and treat several co-morbid conditions, including Cushing’s syndrome and Addison’s disease. A patient’s cortisol levels can also provide insight into his or her overall wellness, including sleep patterns and stress levels. (American Association of Clinical Endocrinologists, 2018).

Is saliva a more accurate measurement of cortisol levels?2023-05-04T16:56:14+00:00

Although blood and saliva contain different amounts of cortisol, both provide accurate measurements. Testing saliva can help monitor cortisol levels over time. Saliva tests are less invasive and more cost-effective than blood tests. Furthermore, patients requiring frequent testing can avoid additional trips to the doctor for blood draws since salivary testing can be performed at home. Therefore, saliva testing is a preferred method of monitoring cortisol levels.

 

Keevil, B. G., MacDonald, P., Macdowall, W., Lee, D. M., Wu, F. C., & NATSAL Team (2014). Salivary testosterone measurement by liquid chromatography tandem mass spectrometry in adult males and females. Annals of clinical biochemistry, 51(Pt 3), 368–378. https://doi.org/10.1177/0004563213506412

What is the most common method of detecting cortisol?2023-05-04T16:55:02+00:00

A blood test has historically been the most common way to detect cortisol. Blood is drawn from an arm vein and sent to a laboratory for analysis. (U.S. National Library of Medicine).

Although blood and saliva contain different amounts of cortisol, both provide accurate measurements. Testing saliva can help monitor cortisol levels over time. Saliva tests are less invasive and more cost-effective than blood tests. Furthermore, patients requiring frequent testing can avoid additional trips to the doctor for blood draws since salivary testing can be performed at home. Therefore, saliva testing is a preferred method of monitoring cortisol levels. (Keevil, 2014)

 

Keevil, B. G., MacDonald, P., Macdowall, W., Lee, D. M., Wu, F. C., & NATSAL Team (2014). Salivary testosterone measurement by liquid chromatography tandem mass spectrometry in adult males and females. Annals of clinical biochemistry, 51(Pt 3), 368–378. https://doi.org/10.1177/0004563213506412

How often should cortisol testing be done?2023-05-04T16:52:20+00:00

Cortisol testing may be recommended at different intervals depending on physicians’ recommendations and treatment plans. Depending on the patient, testing might be needed every few months or once a year. For instance, a patient with Addison’s disease might need more frequent monitoring than a patient with Cushing’s disease. (American Association of Clinical Endocrinologists, 2018)

What is important to know about Cortisol?2023-05-04T16:26:39+00:00

Cortisol is a hormone naturally produced by the adrenal glands. (MedlinePlus Medical Encyclopedia. It is essential because it helps the body respond to stress, regulates blood sugar levels, and supports immunity. Furthermore, cortisol influences weight management, weight gain, and high blood pressure.

 

  1. Adrenal glands: MedlinePlus Medical Encyclopedia. (n.d.). https://medlineplus.gov/ency/article/002219.html
  2. Arafah BM, Nishiyama FJ, Tlaygeh H, Hejal R (2007) Measurement of salivary cortisol concentration in the assessment of adrenal function in critically ill subjects: a surrogate marker of the circulating free cortisol. Clinical Endocrinoly Metabolism 92: 2965-2971.
What are common symptoms of low cortisol levels?2023-05-04T16:29:07+00:00

Fatigue, weakness, nausea, and low blood pressure are common symptoms of low cortisol levels. A woman may also experience irregular periods or missed periods, while a man may experience erectile dysfunction.

 

Inder, W. J., Dimeski, G., & Russell, A. (2012). Measurement of salivary cortisol in 2012 – laboratory techniques and clinical indications. Clinical endocrinology, 77(5), 645–651. https://doi.org/10.1111/j.1365-2265.2012.04508.x

Are there low cortisol risks to wellness?2023-05-04T16:32:25+00:00

Low cortisol levels can increase the risk of wellness issues, including fatigue, weakness, sleep regulation, and dehydration (Lieberman et al., 2005; Liu & Reddy, 2022). Low cortisol levels can sometimes lead to severe co-morbidities, such as Addison’s disease. (National Institute of Diabetes and Digestive and Kidney Diseases, 2017).

 

Lieberman, H. R., Bathalon, G. P., Falco, C. M., Kramer, F. M., Morgan, C. A., 3rd, & Niro, P. (2005). Severe decrements in cognition function and mood induced by sleep loss, heat, dehydration, and undernutrition during simulated combat. Biological psychiatry, 57(4), 422–429. https://doi.org/10.1016/j.biopsych.2004.11.014

Liu, P. Y., & Reddy, R. T. (2022). Sleep, testosterone and cortisol balance, and ageing men. Reviews in endocrine & metabolic disorders, 23(6), 1323–1339. https://doi.org/10.1007/s11154-022-09755-4

National Institute of Diabetes and Digestive and Kidney Diseases. (2017). Adrenal insufficiency and Addison’s disease. https://www.niddk.nih.gov/health-information/endocrine-diseases/adrenal-insufficiency-addisons-disease

What is the threshold for low cortisol levels?2023-05-04T16:50:02+00:00

The threshold for low cortisol levels can vary depending on the individual and the laboratory conducting the test. Validated testing chemistries and lab equipment are specific and unique to each laboratory developed test (LDT) and testing brand, because of this reported lab results on the same patient can vary from one testing brand to the next. However, according to research by Aardal & Holm, 1995, in general, cortisol levels between 0.094–1.551 µg/dL are considered the normal range for morning salivary measurements.

 

Aardal, E., & Holm, A. C. (1995). Cortisol in saliva–reference ranges and relation to cortisol in serum. European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 33(12), 927–932.
https://doi.org/10.1515/cclm.1995.33.12.927

Testing Menu

Easily advance your clinical testing program today with the following SimplyTest® offering:

SimplySTI™

  • Premium STI Plus (blood, urine, saliva)
  • Premium STI (blood, urine)
  • Complete STI Plus (urine, saliva)
  • Complete STI (urine)
  • Oral STI (saliva)

SimplyHPV™

SimplyHormone™

  • Complete Check (saliva)
  • Complete Plus (saliva)
  • Cortisol (saliva)
  • Cortisol 24 (saliva)
  • Testosterone (saliva)
  • Hormone Trio (saliva)
  • Weight Management (saliva)
  • Estrogen Dominance (saliva)
  • Post Menopausal (saliva)
  • Adrenal Fatigue (saliva)

SimplyPERIO™ (saliva)

Laboratory Operations

> In general, test turnaround and results reporting is 24-48 hours after samples have been received by the lab.

> Patient test results are reported and released to the provider from inside your secure portal account.

> Ordering testing supplies is done from inside your provider portal account.

> Hours of laboratory operations
Monday – Friday
8:00 AM to 5:30 PM (CST)

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ACCREDITATIONS

ALIMETRIX, Inc
Molecular testing by Alimetrix, Inc.
CAP #9450297, CLIA #01D2113023

Alimetrix® and SimplyTest® are registered trademarks of Spectrum Solutions, LLC.